The binding site of analgesic receptors has two hydrophobic binding regions in the vicinity of the ionic binding region. One is responsible for agonist activity and the other is responsible for antagonist activity. Which of the following statements is true?

a) The antagonist hydrophobic binding region is closer to the ionic binding region than the agonist hydrophobic binding region.

b) The agonist hydrophobic binding region is closer to the ionic binding region than the antagonist hydrophobic binding region.

c) The antagonist hydrophobic binding region and agonist hydrophobic bind regions are equidistant from the ionic binding region.

d) The relative positions of the hydrophobic regions vary depending on the type of analgesic receptor concerned.