Time Required for Ultrafiltration:Problem 4.10 of “Harrison et al.” Bioseparations Science, Oxford, 2003.Time Required for Ultrafiltration: A protein solution at a concentration of 0.5 g/liter and volume of 1000 liters must be concentrated on a crossflow ultrafilter to a concentration of 10g/liter. The ultrafilter has an area of 100 m2 and operates at 5C with an inlet feed pressure of 16.0 bar, outlet feed pressure of 14.0 bar, and back pressure on the permeate of 1.4 bar. The protein has a molecular weight of 20,000 Da and will not pass through the ultrafiltration membranes. The feed has a viscosity of 1.2 cp. The membrane resistance (Rm) of the UF has benn determined to be 2 x 10-13 cm-1. The Reynolds number for flow within the UF is negligilbe. Determine the time required to perform UF.
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